United now turns its attention back to European play, and Sir Alex Ferguson's team will have plenty to do at Old Trafford on Tuesday if they are to continue their quest for the treble.

On paper the draw seemed to be a good one for United, who avoided Premiership clubs Chelsea and Liverpool, and also would not match them up with traditional European powers Bayern Munich or AC Milan. Roma had not advanced to the quarterfinals of this tournament since it changed names from the European Cup to the Champions League, but the Italian outfit played like they were seasoned veterans of the competition.

They attacked United from the opening whistle, and after Paul Scholes was sent off in the 34th minute for picking up his second booking, Roma took advantage and grabbed the lead before halftime thanks to a goal from Rodrigo Taddei. The one positive that United can take from the game is that Wayne Rooney broke his 17-match goalless streak in Champions League play and temporarily leveled the contest in the second half. Mirko Vucinic wiped out Rooney's tally just six minutes later, and Roma was always going to be the side that came out on top.

Despite the win, Roma have to be somewhat disappointed that they conceded a precious away goal, and that they only bring a one-goal edge into Tuesday's contest. The Italians created many more scoring chances and should have added a few more goals to make the second leg less suspenseful.

United should feel pretty good about its chances despite the deficit, as a 1-0 win in the second leg would be enough to put them through to the semifinals based on away goals. They will not have the services of Scholes, who will miss the game due to suspension, but should have a healthy Louis Saha back in the fold.

The two-match losing skid that the Manchester club is on should not continue. United is returning to the comfort of Old Trafford, and they will no doubt come out playing with more urgency then they showed in Rome last week.

Roma is a very aggressive team that is highly skilled and capable of beating United on its home soil. However, it will be interesting to see how they approach the game, whether they continue to attack as they did in the first leg, or try to defend the one-goal lead that they have. Either way, you can be sure that they are kicking themselves for not finishing off the Red Devils last week when they had the chance.

Tuesday's other contest features Chelsea traveling to Valencia with the two teams on level terms. Chelsea manager Jose Mourinho is looking to guide the Blues to the semifinals for the second time in three years, but Chelsea will have its hands full against a Valencia team that played them to a 1-1 draw at Stamford Bridge in the first leg.

David Silva gave the Spanish side the lead after 30 minutes, but Didier Drogba made sure that Chelsea would come away from the game with no less than a draw as he scored in the 53rd minute to level the match for good.

The two teams played a very evenly matched game in the first leg, and the return leg promises to be just as tight. Valencia's away goal could prove to be big, however, as they produced a similar result in their Round of 16 upset of Inter Milan. They were able to come away with a 2-2 draw against Inter in the first leg, and then locked down the Italian club in the second leg at home, producing a 0-0 draw but moving on because of away goals. Valencia is capable of playing another defensive masterpiece, putting the shackles on the Chelsea attack and playing for a goalless draw. It is a risky tactic that could backfire, but it is not out of the question.

Chelsea should be the more aggressive team offensively, but that could also allow the home side to counter-attack and put the visitors even further in a hole. Chelsea is hoping that midfielder Michael Essien can shake off a knee injury and take part in the game, otherwise there could be a big hole in the center of the Chelsea midfield.

On Wednesday, AC Milan and Bayern Munich enter their return leg on even terms, as the two teams played to an entertaining 2-2 draw in the first leg at the San Siro. After Andrea Pirlo put Milan ahead after 40 minutes, a frantic final 12 minutes saw the teams combine for three goals, including two from Bayern's Daniel van Buyten. With Milan holding a 2-1 lead in the game's final moments, Van Buyten knocked his second goal past Dida to give the German side two big away goals, and a slight edge heading into the return leg at Allianz Arena.

Bayern is a team that is certainly capable of scoring goals, but they have often had a problem keeping them out in this competition. Milan is the more interesting team, one that is capable of playing tight defense, but also a team that can score goals when needed. Kaka has proved to be one of the most dangerous offensive players in the Champions League this season, and Milan will once again lean on its Brazilian playmaker for goals.

Bayern has a number of weapons offensively that can hurt you, but they must be careful not to leave themselves too open in the back.

Wednesday's other fixture seems to be nothing more than a formality as Liverpool returns home to Anfield with a 3-0 lead over a struggling PSV side. The Reds dominated the first leg from start to finish in Holland, with Steven Gerrard scoring the opener midway through the first half, and John Arne Riise and Peter Crouch adding second-half strikes.

PSV showed little in the attack area, and was lost in the back without central defender Alex, who is out with an injury, leaving a number of openings for Liverpool to exploit.

Barring a monumental collapse, Liverpool will go on to the semifinals to meet the winner of the Chelsea and Valencia quarterfinal, and looks to be a good bet to reach the finals for the second time in three years.