Cruz Azul hammered defending champions Pachuca 4-0 to win 6-0 on aggregate while Morelia went through 3-1 on aggregate, despite losing 1-0 to America.

Cruz Azul, already 2-0 ahead from the first leg, quickly increased their advantage when Argentine striker Cesar Delgado scored in the 13th minute.

Jared Borgetti snapped up a rebound for the second in the 32nd minute and Uruguayan Richard Nunez scored twice in three minutes midway through the second half to set up a quarter-final with Atlante.

The defeat avoided a possible fixture pile-up for CONCACAF champions Pachuca, who take part in the Club World Cup in Japan next month.

Enrique Estrada scored America's only goal three minutes before halftime against Morelia.

The Eagles missed a chance to cut the deficit further when Hernan Lopez missed a penalty in the 54th minute.

Morelia will face Santos Laguna in the last eight, while Guadalajara take on San Luis and Toluca play Pumas UNAM.